Keitumetse Shadrack Semakane was born at Mabeskraal, on 10 May 1956.
He attended Rakoko High School at Mabeskraal in North West and matriculated in 1976.
In 1980, he obtained a Junior Secondary Teachers Course (JSTC) from Batswana Teachers Training College. Between 1981 and 1987, he obtained a BA and B Ed from UNISA. Between 1993 and 1994, Keitu obtained certificates in Basic Principles in Public Relations (with distinction) and Public Relations Practice.
In 1994, he completed an M Ed at the University of Pochefstroom and in 2004. He successfully completed the Senior Management Programme (with distinction) at the University of Pretoria.
Keitu has worked as a temporary teacher from 1977 to 1978 and as teacher from 1981 to mid-1982. He became a lecturer of Educational Studies at Hebron College of Education, between 1987 and 1992.
Keitu has vast experience in the media environment. He worked for SABC as producer/translator and announcer. He freelanced for Radio Mmabatho and Mmabatho Television as news presenter.
Between 1992 and 1995, he worked as Public Relations Officer with the Department of Education in North West. One of his duties was to determine the internal and external communication policy of the department.
In 1995, he joined GCIS Johannesburg Regional Office as Director: Communication, a position he held for one year. In 1996, he moved to head office as Director: Corporate Services until 1998. In 1999, Keitu moved to the position of Director: Human Resources. In 2002 he was promoted to Chief Director: Corporate Services.
He is married to Mmamokgethi and they have three daughters, Orefemetse, Rebaneilwe and Realeboga and a son, Reotshepile.